Topic information for: Pathology
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Penny06:40
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I was recently reading my pathology report and it said Triple Negative Breast Cancer grade 9 (3+3+3) on the nottingham scale - my tumor was about 6cm but had not spread to any lymph nodes - what is grade 9?
Asked by anonymous
Survivor since 2009-
anonymous
Family Member or Loved One
Hi Blair,
I was curious about your question and did a bit of research. Here is the best answer I came up with. It was given by:
Kevin R. Fox, MD, Assistant Director, Clinical Affairs and Associate Professor of Hematology/Oncology at the Abramson Cancer Center of the University of...
4 comments 3Hi Blair,
I was curious about your question and did a bit of research. Here is the best answer I came up with. It was given by:
Kevin R. Fox, MD, Assistant Director, Clinical Affairs and Associate Professor of Hematology/Oncology at the Abramson Cancer Center of the University of Pennsylvania, responds:
The Nottingham histologic score is simply a scoring system to assess the "grade" of breast cancers.
It is a total score based on 3 different sub-scores. The 3 sub-scores are assigned based on 3 components of how the breast cancer cells look under a microscope. (The details of these 3 components are not critical for you to understand). Each of the 3 components is assigned a sub-score of 1, 2, or 3, with 1 being best and 3 being worst. Once the 3 sub-scores are added, a Nottingham score is obtained: the minimum score possible is 3 (1+1+1) and the maximum possible is 9 (3+3+3).
A histologic grade of III is assigned to any patient with a Nottingham score of 8 or 9. Grade I refers to Nottingham scores of 3, 4, and 5, while Grade II refers to Nottingham scores of 6 and 7.
In the end, the Nottingham score and histologic grades are not very useful in the big picture, as they do not alter final overall treatment recommendations. High-score cancers tend to relapse more often than low-score cancers. Ultimately, however, we don't use the score in making clinical decisions.
I hope that this helps clear up any confusion. I wish you the best.
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anonymous
Survivor since 2010
Do you have a family history? If yes, I suggest genetic testing for the BRCA gene mutation.
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I had a lumpectomy of both breast 1 week ago, yesterday was my post op visit my pathology results where not in, but I have been told I will be getting radiation. How can they tell without the results?
Asked by anonymous
Learning About Breast Cancer- View all 4 answers
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anonymous
Patient
They may have been able to tell by the size and/or area of the lump? Just a guess.
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anonymous
Learning About Breast Cancer
It's often standard procedure with a lumpectomy. If your tumor was very small then it may be more of a preventive measure.
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I have an ultrasound guided biopsy on Monday and my Dr. said I should hear something in 2-3 days after. How long does it actually take to get the pathology report and test results?
Asked by anonymous
Family Member or Loved One- View all 10 answers
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anonymous
Learning About Breast Cancer
An MRI guided biopsy is different than an ultrasound guided biopsy. An ultrasound biopsy is not that bad really, it only takes about 15 min. Good luck and just keep in mind that most biopsies come back not showing any cancer.
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anonymous
Survivor since 2007
Aunia, we all understand the angst of the wait. I had to wait 3 days. I also had an ultrasound guided biopsy. It didn't take that long and like Diana, I was just a little sore afterward.... remember to put some ice on the area. So many of these are benign, so don't worry yourself sick about...
Comment 1Aunia, we all understand the angst of the wait. I had to wait 3 days. I also had an ultrasound guided biopsy. It didn't take that long and like Diana, I was just a little sore afterward.... remember to put some ice on the area. So many of these are benign, so don't worry yourself sick about it. Your doctor is just being proactive and looking out for your best interest. I have a huge circle of friends and many of them have had this type of test..... of them all, I am the only one whose test came out positive. Hang in there Aunia.... we are all here to help support one another. Blessings to you, Sharon
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I was Reading my post operative pathology report and found out I jumped from grade 2 to grade 3. Feeling like it's no longer curable. How do you cope?
Asked by anonymous
Stage 2A Patient- View all 9 answers
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anonymous
Stage 4 Patient
I understand hoe you're feeling. I was diagnosed last year at 49 with stage 3C breast cancer. I was scared beyond belief. The cancer was also in my chest wall and 13 lymph nodes with some breaking outside the node. Went through 8 rounds of chemo then a bilateral mastectomy. They discovered that...
2 comments 8I understand hoe you're feeling. I was diagnosed last year at 49 with stage 3C breast cancer. I was scared beyond belief. The cancer was also in my chest wall and 13 lymph nodes with some breaking outside the node. Went through 8 rounds of chemo then a bilateral mastectomy. They discovered that chemo hadn't helped as much as they thought. So....I switched chemo drugs and had 8 more 3 weeks after my surgery. Then 33 radiation treatments. I'm on tamoxifen now and I'm happy to say I'm in remission!!! It wasn't easy. You just take it one day at a time. If that's too much....one hour at time. You'll get to the other side of all this. And we're cheering you on.....every step of the way!!!!!!
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anonymous
Survivor since 2007
I, too, had a disappointment in my post-op pathology report. After hearing from my surgeon right after my surgery that all 5 sentinel nodes were clear.... one came back positive in the pathology report. I know how you feel, as it is a huge let-down and you MOMENTARILY watch your life pass...
Comment 6I, too, had a disappointment in my post-op pathology report. After hearing from my surgeon right after my surgery that all 5 sentinel nodes were clear.... one came back positive in the pathology report. I know how you feel, as it is a huge let-down and you MOMENTARILY watch your life pass before your eyes. You just get back up on the pony and keep on riding! The shock of this will pass.... you will get better, you will get well, you will be ok. You got through your treatment, and charge ahead with your life. This is just a piece of the puzzle of your disease. This is not charting your course of life. There are a vast majority of us who are alive and well years after beating breast cancer. You just work on being one of us. I swear a positive attitude will do more for you than 50 gallons of tears you could cry over this small fact. You reaction should be.... SO WHAT! Kick booty darlin' do not let this get you down. Fight like a girl and you will be a winner.
Hang in there, much love and strength, take care, Sharon
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How do you read and understand a pathology report? My doctor wasnt much help.
Asked by anonymous
Learning About Breast Cancer- View all 6 answers
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anonymous
Survivor since 2007
Brandi,
If you can share it with us, we could help decipher it. They usually tell the type, location, size, stage, grade... which you already shared with us. Many times, if you can talk to a nurse in the doctor's office, they can take it down a notch for you. In some practices, or clinics,...3 comments 2Brandi,
If you can share it with us, we could help decipher it. They usually tell the type, location, size, stage, grade... which you already shared with us. Many times, if you can talk to a nurse in the doctor's office, they can take it down a notch for you. In some practices, or clinics, they have an R.N. who helps guide you through the process. They have lots of experience explaining what the pathology report or any other report says. Be sure to take somebody with you when you have other --meet-the-doctor-- appointments. It is freaking comfusing to take it all in. Hang in there..... take care, Sharon -
anonymous
Stage 2A Patient
I sat down at the computer and googled each term I didn't understand. I made notes and asked about anything that I still dint understand.
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I have micropapillary breast cancer. The Internet isn't very helpful. My surgeon acts like the diagnosis isn't a big deal, but I had a recurrence less than 1 yr from a double mastectomy. Has anyone else been diagnosed with this?
Asked by anonymous
Learning About Breast Cancer-
anonymous
Survivor since 2011
It sounds like it might be time for a second or third opinion. I would bring peace of mind that you are doing the right thing or the information that you need to change the course of treatment.
Comment 1 -
anonymous
Learning About Breast Cancer
My husband and I have decided that if the cancer comes back we have to go somewhere else for treatment. Unfortunately we live in a medium sized city with basically only 3-4 options and my insurance only covers this one group of drs. We will do what it takes to save my life, I just pray it doesn't...
2 comments 0My husband and I have decided that if the cancer comes back we have to go somewhere else for treatment. Unfortunately we live in a medium sized city with basically only 3-4 options and my insurance only covers this one group of drs. We will do what it takes to save my life, I just pray it doesn't come at the cost of financial ruin. I have enough to feel guilty about as it is! :-)
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I just noticed I have "evidence of angiolymphatic invasion" on my pathology report. It sounds like this is not good, but my doctor told me I am Stage 1 and did not address the angiolymphatic invasion. I was feeling positive but now am stressed.
Asked by anonymous
Learning About Breast Cancer-
anonymous
Stage 1 Patient
I'm not a dr, but I think it means that there was potential of lymph invasion, not that there was. Please question this with your dr so you know for sure. Prayers to you.
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anonymous
Survivor since 2013
If you're not happy with the way your report was addressed seek another opinion.
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anyone had ER neg / PR pos/ HER2 neg? Does this mean I am HR or not? Diagnosed 3 days ago. seeing doctor first time monday.
Asked by anonymous
Learning About Breast Cancer-
anonymous
Survivor since 2013
If I recall since you're Pr+ it means your tumor was being fed by progesterone. Make sure and ask your doctor when you see them and they can clarify that as we aren't doctors here.
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